• Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis

    1. Markus Mund
    2. Aline Tschanz
    3. Yu-Le Wu
    4. Felix Frey
    5. Johanna L. Mehl
    6. Marko Kaksonen
    7. Ori Avinoam
    8. Ulrich S. Schwarz
    9. Jonas Ries
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    Annotation by Prachee Avasthi Recommended Reading

    This is an incredible study using super resolution imaging and mathematical modeling to propose a new model of clathrin coat assembly (the cooperative curvature model) that challenges both the constant curvature and constant area (flat membrane preassembly of clathrin) assembly models.

  • Pericentrin is a Kinesin-1 Activator that Drives Centriole Motility

    1. Matthew R. Hannaford
    2. Rong Liu
    3. Neil Billington
    4. Zachary T. Swider
    5. Brian J. Galletta
    6. Carey J. Fagerstrom
    7. Christian Combs
    8. James R. Sellers
    9. Nasser M. Rusan
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    Annotation by Prachee Avasthi Recommended Reading

    Important study showing centriole migration of mother centrioles in fly neuroblasts during interphase is mediated by kinesin-1 (as cargo) and pericentrin-like protein. The actin cytoskeleton has been implicated in this but is not responsible in this context.

  • Proteomic Dissection of a Giant Cell

    1. Athena Lin
    2. Paul D. Piehowski
    3. Chia-Feng Tsai
    4. Tatyana Makushok
    5. Lian Yi
    6. Ulises Diaz
    7. Connie Yan
    8. Diana Summers
    9. Pranidhi Sood
    10. Richard D. Smith
    11. Tao Liu
    12. Wallace F. Marshall
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  • Islet primary cilia motility controls insulin secretion

    1. Jung Hoon Cho
    2. Zipeng A. Li
    3. Lifei Zhu
    4. Brian D. Muegge
    5. Henry F. Roseman
    6. Toby Utterback
    7. Louis G. Woodhams
    8. Philip V. Bayly
    9. Jing W. Hughes
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  • Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions

    1. Eden Yifrach
    2. Duncan Holbrook-Smith
    3. Jérôme Bürgi
    4. Alaa Othman
    5. Miriam Eisenstein
    6. Carlo W.T Van Roermund
    7. Wouter Visser
    8. Asa Tirosh
    9. Chen Bibi
    10. Shahar Galor
    11. Uri Weil
    12. Amir Fadel
    13. Yoav Peleg
    14. Hans R Waterham
    15. Ronald J A Wanders
    16. Matthias Wilmanns
    17. Nicola Zamboni
    18. Maya Schuldiner
    19. Einat Zalckvar
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